Dr. Curt Connors First appeared in the Amazing Spider-Man issue #6, and has more or less been around in one form or another ever since. Connors, a gifted surgeon, was enlisted into the Army and lost his right arm during the war(Originally Korea, perhaps.) Upon returning to civilian life he began experimenting with reptile DNA in hopes to harness the ability to regrow limbs. He regrew his arm.....and this happened:
....not quite the desired effect.
Since his introduction the Lizard has battled Spider-man numerous times. While in his human form Connors has become a close ally to the web head. The character hasn't gotten a lot of love lately, and he's been called out dated and two-dimensional. I beg to differ. While the sympathetic scientist turned evil plot is one of the most well told, at the time of his creation it wasn't. It wasn't common for superheros to have villains they cared about. It was something new and fresh.
I believe with a creator that can give the Lizard motivation and direction, he can become an A list villain again. I'm tired of stories where Doc Connors gets turned and attacks spider-man, and that's the extent of of his appearance. No one knows what to do with him, and it's wasted potential. Give him more of a Jekyll/Hyde persona, rather then the Hulk syndrome. Have the Lizard consciously plot against Connors, He doesn't lose his intellect when he transforms, only becomes evil. A lot could be done with that. and please keep him out of purple pants......